Infecciones relacionadas con el embarazo

Información clínica

El término TORCH engloba todas las enfermedades infecciosas que pueden transferirse de la madre al niño en el útero, durante o después del parto a través de la infección vertical. Incluye la Toxoplasma gondii, el virus de la rubéola, el citomegalovirus (CMV), el virus del herpes simple (VHS) y otros patógenos como Chlamydia trachomatis, parvovirus B19, Treponema pallidum y el virus de la varicela-zóster (VVZ). Durante el embarazo, las infecciones primarias son de especial preocupación, ya que se asocian a un mayor riesgo de daños al feto.

Diagnóstico

El análisis de anticuerpos contra los parámetros de las TORCH es una parte esencial de los cuidados prenatales, peri y posnatales. Las pruebas permiten analizar el estado inmunitario de la madre y los riesgos a los que se puede exponer
un embarazo existente. Las pruebas para diagnosticar las TORCH se suelen realizar durante el primer trimestre del embarazo, pero también se pueden llevar a cabo en el recién nacido si hay indicios de una infección. El análisis inicial de anticuerpos contra patógenos de las TORCH tiene como objetivo determinar el estado inmunitario de la madre para poder diferenciar entre infecciones primarias agudas e infecciones pasadas o reactivaciones durante el curso del embarazo. Si se diagnostican a tiempo, las infecciones TORCH pueden tratarse en parte de forma eficaz, reduciendo el riesgo de defectos congénitos o pérdida del feto.

Archivo

Cribado serológico durante el embarazo: T o R C H

Techniques

Method
Parameter
Substrate
Species
EUROLINE
positive control serum: IgG, human, 50x concentrated
for Treponema pallidum
EUROLINE
positive control serum: IgM, human, 50x concentrated
for Treponema pallidum
WESTERNBLOT
antibodies against Treponema pallidum
IgG positive control
WESTERNBLOT
antibodies against Treponema pallidum
IgM positive control
EUROLINE
Treponema pallidum
(TpN15, TpN17, TmpA, TpN47 separately)
EUROLINE
WESTERNBLOT
Treponema pallidum
Westernblot
ELISA
Treponema pallidum
antigen-coated
microplate wells
ELISA
Treponema pallidum
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
Treponema pallidum
Screen ELISA
antigen-coated
microplate wells
IIFT
Treponema pallidum
(FTA-ABS)
bacterial
smear
verification BIOCHIP
(2 BIOCHIPs per field)
T. pallidum
WESTERNBLOT
EUROLINE-WB
Treponema pallidum
plus cardiolipin
Westernblot
ELISA
CSQ pair of controls
anti-Treponema pallidum (IgG)
ELISA
Treponema pallidum
antibody determination in CSF
antigen-coated
microplate wells
IIFT
Treponema pallidum
(FTA-ABS)
bacterial
smears
verification BIOCHIP
(3 BIOCHIPs per field)
T. pallidum
T. phagedenis
ELISA
Chlamydia trachomatis
antigen-coated
microplate wells
ELISA
Chlamydia trachomatis
antigen-coated
microplate wells
ELISA
Chlamydia trachomatis
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Anti-Chlamydia MIF
Chlamydia trachomatis
Chlamydia pneumoniae
Chlamydia psittaci
4 BIOCHIPs per field:
elementary bodies
and non-infected cells

EU 40
EU 40
EU 40
IIFT
Anti-Chlamydia MIF EUROPattern
Chlamydia trachomatis
Chlamydia pneumoniae
Chlamydia psittaci
4 BIOCHIPs per field:
elementary bodies
and non-infected cells

EU 40
EU 40
EU 40
IIFT
Chlamydia trachomatis
elementary bodies (MIF)
non-infected cells
(2 BIOCHIPs per field)
EU 40
EU 40
ChLIA
IDS TOXO Control Set 1
3 x 1.5mL Control 1/2
ELISA
Toxoplasma gondii
antigen-coated
microplate wells
ELISA
Toxoplasma gondii
antigen-coated
microplate wells
ELISA
Toxoplasma gondii
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
Toxoplasma gondii Screen
antigen-coated
microplate wells
IIFT
Toxoplasma
gondii
protozoan
smear
Toxoplasma
gondii
IIFT
Toxoplasma gondii
EUROPattern
Protozoa-
smear
Toxoplasma
gondii
ChLIA
IDS TOXO IgG 1
antigenic coated magnetic particles
ChLIA
IDS TOXO IgM 1
antigenic coated magnetic particles
ChLIA
IDS TOXO Avidity Control Set 1
3 x 1.0mL Control 1/2
ELISA
Toxoplasma gondii
avidity determination
antigen-coated
microplate wells
ChLIA
IDS TOXO IgG Avidity 1
antigenic coated magnetic particles
EUROLINE
"TO.R.C.H. 10"
(Toxoplasma gondii, Rubella virus, CMV,
HSV-1, HSV-2, Bordetella pertussis, Chlamydia trachomatis,
Parvovirus B19, Treponema pallidum, VZV separately)
EUROLINE
EUROLINE
positive control serum: IgG, human, 50x concentrated
for TO.R.C.H. Profile
EUROLINE
positive control serum: IgM, human, 50x concentrated
for TO.R.C.H. Profile
EUROLINE
"TO.R.C.H. Profile"
(Toxoplasma gondii, Rubella virus,
CMV, HSV-1, HSV-2 separately)
EUROLINE
EUROLINE
"TO.R.C.H. Profile"
(Toxoplasma gondii, ROP1, Rubella virus,
CMV, HSV-1, HSV-2 separately)
EUROLINE
ELISA
CSQ pair of controls
anti-Toxoplasma gondii (IgG)
ELISA
Toxoplasma gondii
antibody determination in CSF
antigen-coated
microplate wells
PCR
EURORealTime HSV-1/2
EUROArray
EUROArray HSV1/2 VZV
WESTERNBLOT
antibodies against Herpes simplex virus (HSV)
IgG positive control
ChLIA
Anti-Herpes simplex virus 1 ChLIA (IgG)
Antigen-coated magnetic particles
ChLIA
Control set Anti-Herpes simplex virus 1 ChLIA (IgG)
2 x 0.5 ml control 1/2
ELISA
CSQ pair of controls
anti-HSV-1/2 Pool (IgG)
ChLIA
IDS HSV 1/2 IgM Control Set 1
3 x 1.5mL Control 1/2
WESTERNBLOT
EUROLINE-WB
Herpes simplex virus 1 (HSV-1)
plus HSV-2 type-specific
glycoprotein G2
Westernblot
ELISA
Herpes simplex virus
(HSV-1/2 Pool)
antigen-coated
microplate wells
ELISA
Herpes simplex virus
(HSV-1/2 Pool)
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Herpes simplex virus
(HSV-1/2 Pool)
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS HSV 1/2 IgM 1
antigenic coated magnetic particles
ELISA
Herpes simplex virus 1
(HSV-1)
antigen-coated
microplate wells
ChLIA
IDS HSV-1 IgG 1
antigenic coated magnetic particles
ChLIA
Anti-Herpes simplex virus 2 ChLIA (IgG)
Antigen-coated magnetic particles
ChLIA
Control set Anti-Herpes simplex virus 2 ChLIA (IgG)
2 x 0.5 ml control 1/2
ELISA
Herpes simplex virus 2
(HSV-2)
antigen-coated
microplate wells
ChLIA
IDS HSV-2 IgG

1
antigenic coated magnetic particles
ChLIA
IDS HSV 1/2 IgG Control Set 1
3 x 1.5mL Control 1/2
EUROLINE
positive control serum: IgG, human, 50x concentrated
for CMV
EUROLINE
positive control serum: IgM, human, 50x concentrated
for CMV
ChLIA
IDS CMV Control Set 1
3 x 1.5mL Control 1/2
EUROLINE
EUROLINE Cytomegalovirus
(CMV)
(gpB, p150, p65, p52, CMV lysate separately)
EUROLINE
EUROLINE
EUROLINE Cytomegalovirus
(CMV)
( p150, p65, p52, CMV lysate separately)
EUROLINE
ELISA
Cytomegalovirus
(CMV)
antigen-coated
microplate wells
ELISA
Cytomegalovirus (CMV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS CMV IgG 1
antigenic coated magnetic particles
ChLIA
IDS CMV IgM 1
antigenic coated magnetic particles
ChLIA
IDS CMV Avidity Control Set 1
3 x 1.0mL Control 1/2
ELISA
Cytomegalovirus (CMV)
avidity determination
antigen-coated
microplate wells
ChLIA
IDS CMV IgG Avidity 1
antigenic coated magnetic particles
ELISA
Cytomegalovirus (CMV) p52
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
Cytomegalovirus
(CMV) gB
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Cytomegalovirus (IgG)
ELISA
Cytomegalovirus (CMV)
antibody determination in CSF
antigen-coated
microplate wells
EUROLINE
positive control serum: IgG, human, 50x concentrated
for parvovirus
EUROLINE
positive control serum: IgM, human, 50x concentrated
for parvovirus
ChLIA
IDS Parvovirus B19 Control Set 1
3 x 1.5mL Control 1/2
EUROLINE
Parvovirus B19
(VP1, VLP, VP2, NS1 separately)
EUROLINE
ELISA
Parvovirus
B19
antigen-coated
microplate wells
ELISA
Parvovirus B19
incl. IgG/RF absorbent
antigen-coated
microplate wells
ChLIA
IDS Parvovirus B19 IgG 1
antigenic coated magnetic particles
ChLIA
IDS Parvovirus B19 IgM 1
antigenic coated magnetic particles
ChLIA
IDS Rubella Control Set 1
3 x 1.5mL Control 1/2
WESTERNBLOT
Rubella virus
Westernblot
ELISA
Rubella virus
antigen-coated
microplate wells
ChLIA
IDS Rubella IgG
1
antigenic coated magnetic particles
ChLIA
IDS Rubella IgM 1
antigenic coated magnetic particles
ChLIA
IDS Rubella Avidity Control Set 1
3 x 1.0mL Control 1/2
ELISA
Rubella virus
avidity determination
antigen-coated
microplate wells
ChLIA
IDS Rubella IgG Avidity 1
antigenic coated magnetic particles
ELISA
Rubella virus glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-Rubella virus (IgG)
ELISA
Rubella virus
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus
(VZV)
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Varicella zoster virus
(VZV)
infected cells
EU 168
ChLIA
IDS VZV IgG 1
antigenic coated magnetic particles
ChLIA
IDS VZV IgM 1
antigenic coated magnetic particles
ELISA
Varicella zoster virus (VZV)
avidity determination
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV) glycoprotein
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
CSQ pair of controls
anti-VZV (IgG)
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Varicella zoster virus (VZV)
antibody determination in CSF
antigen-coated
microplate wells
ELISA
Zika virus (ZIKV)
antigen-coated
microplate wells
ELISA
Zika virus (ZIKV)
antigen-coated
microplate wells
ELISA
Zika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
ELISA
Zika virus (ZIKV)
incl. IgG/RF absorbent
antigen-coated
microplate wells
IIFT
Zika virus (ZIKV)
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Zika virus (ZIKV) EUROPattern
infected and non-
infected cells
(2 BIOCHIPs per field)
EU 14
IIFT
Arbovirus Fever Mosaic 2
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
IIFT
Arbovirus Fever Mosaic 2 EUROPattern
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
6 BIOCHIPs per field:
infected cells
infected cells
infected cells

EU 14
EU 14
EU 14
IIFT
Arbovirus Profile 3
upper row :
Zika virus (ZIKV)
Chikungunya virus (CHIKV)
Dengue virus types 1 - 4 (DENV)
bottom row:
TBE virus (TBEV)
West Nile virus (WNV)
Japanese encephalitis virus (JEV)
Yellow fever virus (YFV)


infected cells
infected cells
infected cells

infected cells
infected cells
infected cells
infected cells


EU 14
EU 14
EU 14

EU 14
EU 14
EU 14
EU 14
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